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Urine sample
Urine sample


Acid mucopolysaccharides

Definition:

Acid mucopolysaccharides is a test that measures the amount of mucopolysaccharides released into the urine over a 24-hour period.

Mucopolysaccharides are long chains of sugar molecules found throughout the body, often in mucus and in fluid around the joints.



Alternative Names:

AMP; Dermatan sulfate - urine; Urine heparan sulfate; Urine dermatan sulfate; Heparan sulfate - urine



How the test is performed:

A 24-hour urine sample is needed.

  • On day 1, urinate into the toilet when you get up in the morning.
  • Afterwards, collect all urine in a special container for the next 24 hours. Keep it in the refrigerator or a cool place during the collection period.
  • On day 2, urinate into the container when you get up in the morning.
  • Cap the container. Label the container with your name, the date, the time of completion, and deliver it to the laboratory or your health care provider as soon as possible.


How to prepare for the test:

There is no special preparation needed.



How the test will feel:

The test involves only normal urination, and there is no discomfort.



Why the test is performed:

This test is done to diagnose a rare group of genetic disorders called mucopolysaccharidoses, including Hurler syndrome .

This test is usually only done in infants who have a family history of one of these disorders.



Normal Values:

Normal levels vary with age and from lab to lab. Talk to your doctor about the meaning of your specific test results.



What abnormal results mean:

Abnormally high levels are a sign of mucopolysaccharidosis. Further tests are needed to determine the specific type of mucopolysaccharidosis.




Review Date: 5/12/2011
Reviewed By: Frank A. Greco, M.D., Ph.D., Director, Biophysical Laboratory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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