In This SectionTexas Health Research & Education Institute
Disease or Condition
Heart / Chest Pain
Prospective Multicenter Imaging Study for Evaluation of Chest Pain (Heart/Chest Pain)
This study is designed to compare different, routinely-performed heart tests, such as exercise electrocardiogram (ECG), stress echocardiogram (echo), or stress nuclear test, and coronary computed tomography angiography (CTA), in identifying heart disease and reducing future heart problems.
New or worsening chest pain syndrome or equivalent symptoms suspicious for clinically significant CAD.
No prior evaluation for this episode of symptoms.
Planned non-invasive testing for diagnosis.
Men age > 55 and women age =65 years.
If age in men 45 - 54 or women 50 - 64 years, then must have increased probability of CAD due to EITHER:
A. Diabetes Mellitus (DM) requiring medical treatment OR Peripheral Arterial Disease (PAD) defined as documented >50% peripheral arterial stenosis treated medically or invasively OR cerebrovascular disease (stroke, documented > 50% carotid stenosis treated medically or invasively) OR
B. At least one of the following cardiovascular risk factors:
ongoing tobacco use, hypertension, abnormal ABI defined as less than <0.9, dyslipidemia.
Serum creatinine < 1.5 mg/dL within the past 90 days.
Negative urine/serum pregnancy test for female subjects of child-bearing potential.
Must be able to speak, read and write English.
Diagnosed or suspected ACS requiring hospitalization or urgent or emergent testing; Elevated troponin or CK-MB.