Charting the Path and Processes of Digestion
Health and Well Being
January 07, 2026
Charting the Path and Processes of Digestion
Father feeding son

Bowel health—often referred to as digestive or gastrointestinal health—is integral to the general wellbeing of every individual. The gastrointestinal tract is complex yet fascinating, with intricate structures and processes that play a vital role in sustaining life. This system includes the mouth, esophagus, stomach, small intestine, and large intestine, each contributing uniquely to the body’s ability to process food, absorb nutrients, and eliminate waste.

“The gut is the powerhouse that drives the body’s overall health,” says Sheikh A. Saleem, M.D., gastroenterologist at Texas Health Digestive Specialists, a Texas Health Physicians Group practice in Allen. “Every stage of digestion, from the mouth to the colon, plays a critical role in maintaining overall health.”

Mouth, Esophagus, and Stomach

Digestion begins the moment food enters the mouth. Chewing breaks food into smaller pieces, while saliva mixes with it to initiate chemical breakdown. Saliva contains enzymes such as amylase, which begin digesting carbohydrates before food even reaches the stomach.

Certain conditions can interfere with this seemingly simple process. Sjogren’s syndrome, an autoimmune disorder, reduces saliva production and causes dry mouth, making chewing and swallowing difficult.

Sheikh A. Saleem, M.D.
Sheikh A. Saleem, M.D.

“Even something as simple as saliva production is vital,” Dr. Saleem explains. “When it’s disrupted, patients can experience significant discomfort and nutritional challenges.”

Once swallowed, food travels down the esophagus. This muscular tube uses coordinated contractions, called peristalsis, to push food toward the stomach. Disorders such as achalasia, eosinophilic esophagitis, or chronic acid reflux can disrupt this process. Gastroesophageal reflux disease (GERD), in particular, is common and can cause heartburn, chest discomfort, or even bleeding. Left untreated, GERD may lead to Barrett’s esophagus and increase the risk of esophageal cancer.

“Heartburn should never be ignored. Chronic acid reflux can damage the esophagus and, in severe cases, increase cancer risk,” notes Dr. Saleem.

In the stomach, food is churned and mixed with gastric acid and enzymes. This environment is designed to break food down into smaller particles for nutrient absorption later. However, stress, infections such as Helicobacter pylori, or medications—including opioids and certain weight‑loss drugs—can interfere with stomach function. Gastroparesis, a condition where the stomach empties too slowly, can cause bloating, nausea, and vomiting.

“We often see patients whose stomachs don’t empty properly. Recognizing these symptoms early allows us to intervene before complications arise,” Dr. Saleem emphasizes.

The Small Intestine: Absorption and Balance

After leaving the stomach, food enters the small intestine, which is divided into the duodenum, jejunum, and ileum. Here, nutrients are absorbed into the bloodstream. Pancreatic enzymes, bile from the liver, and the gut microbiome all contribute to breaking food down into usable components such as glucose, amino acids, vitamins, and minerals.

Celiac disease, a genetic autoimmune condition, occurs when gluten triggers the immune system to attack the lining of the small intestine. This damage reduces nutrient absorption and can lead to diarrhea, weight loss, and malnutrition.

“Nutrient absorption is one of the cornerstones of health. When diseases like celiac interfere, the consequences can be profound if left untreated,” Dr. Saleem says.

The small intestine also hosts billions of microorganisms that form the gut microbiome. This community of bacteria, fungi, and other microbes plays a critical role in digestion, immune function, and even mental health. Disruptions to this balance—through antibiotics, poor diet, or illness—can contribute to conditions such as irritable bowel syndrome (IBS).

The Large Intestine: Water and Waste

The large intestine, or colon, absorbs water and electrolytes from digested food, forming solid waste for elimination. It also houses a diverse microbiome that continues to influence health.

Autoimmune conditions such as Crohn’s disease and ulcerative colitis attack the colon lining, causing inflammation, bleeding, and sometimes strictures or blockages. These conditions can significantly impact quality of life and, in severe cases, increase cancer risk.

IBS, while not life‑threatening, is a complex disorder involving the gut‑brain axis and microbiome imbalance. Symptoms include abdominal cramps, bloating, constipation, or diarrhea.

“Patients often think IBS is ‘just in the head,’ but it’s a complex interplay between the brain, gut, and microbiome,” Dr. Saleem clarifies.

The Importance of Timely Evaluation

Digestive disorders often begin with subtle symptoms—heartburn, bloating, or changes in bowel habits—that patients may dismiss. However, these signs can indicate underlying conditions requiring medical attention. Gastroenterologists use diagnostic tools such as colonoscopy and endoscopy to evaluate the gastrointestinal tract, detect abnormalities, and intervene early.

“Timely evaluation by a GI specialist can prevent complications and dramatically improve both quality and quantity of life,” Dr. Saleem advises.

Colonoscopy, for example, allows physicians to identify and remove precancerous polyps, reducing the risk of colorectal cancer. Endoscopy enables direct visualization of the esophagus, stomach, and small intestine, helping diagnose conditions like GERD, ulcers, or celiac disease.

Lifestyle and Preventive Care

Beyond medical interventions, lifestyle choices play a significant role in digestive health. A balanced diet rich in fiber, lean proteins, and healthy fats supports regular bowel function and nourishes the microbiome. Hydration is equally important, as water aids digestion and prevents constipation.

Regular physical activity promotes healthy peristalsis, while stress management reduces the risk of acid reflux and functional bowel disorders. Avoiding tobacco and limiting alcohol also protect the gastrointestinal tract from damage.

Routine screenings are essential, especially for individuals over 45 or those with a family history of colorectal cancer. Early detection saves lives.

The Bigger Picture: Digestive Health and Overall Wellness

The gastrointestinal tract does more than process food—it influences immunity, metabolism, and even mental health. Research continues to uncover connections between the microbiome and conditions such as depression, anxiety, and autoimmune disease.

Maintaining digestive health is therefore not just about avoiding discomfort; it is about supporting the body’s overall resilience.

“Every patient’s digestive health journey is unique. My role is to listen carefully, provide clear guidance, and tailor treatment plans that fit both medical needs and lifestyle,” Dr. Saleem emphasizes.

From the mouth to the colon, the digestive system is a remarkable network of organs and processes that sustain life. When functioning well, it allows the body to thrive. When disrupted, it can lead to discomfort, disease, and even life‑threatening complications.

Through preventive care, timely evaluation, and patient‑centered treatment, Texas Health gastroenterologists can help individuals protect their digestive health and, in turn, their overall wellbeing.

Find a gastroenterologist near you at TexasHealth.org or take our acid reflux assessment or our colorectal cancer assessment today to learn more about your digestive health and whether it’s time to talk to a digestive health specialist.

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