1984: Texas Back Institute partners, S.H. Hockshuler, M.D., R.D. Guyer, M.D., and R.F. Rashbaum, M.D., establish one of the first independent nonprofit spine research and education centers in North America — the North Texas Spine Research Foundation.
1990: The Research Foundation hires T.D. Franklin Jr., Ph.D., as President and CEO, expands its staff, and is renamed the Texas Back Institute Research Foundation (TBIRF).
1992: TBIRF is designated a 501(c)(3) non-profit Private Operating Foundation.
1994: Growing rapidly, TBIRF becomes the Institute for Spine and Biomedical Research (ISBR), is designated a Medical Research Organization, and moves into a new facility at Presbyterian Hospital of Plano.
1998: ISBR becomes Texas Health Research Institute (THRI), a member organization of Texas Health Resources.
1999: THRI manages continuing medical education (CME) for the 4,500 physicians affiliated with Texas Health hospitals.
THRI inaugurates the Presbyterian Institute for Minimally Invasive Technology (PIMIT), a research and training center at Presbyterian Hospital of Dallas (now Texas Health Presbyterian Hospital Dallas). The facility, now known as Texas Health Minimally Invasive Technology Center, trains physicians and their teams from across the U.S.
2001: THRI coordinates systemwide research compliance activities, as well as clinical oncology studies for Harris Methodist Hospital Fort Worth. THRI is awarded systemwide accreditation for CME activities through Texas Medical Association.
2004: THRI is awarded systemwide national accreditation for CME activities through the Accreditation Council for Continuing Medical Education.
2005: The Texas Health Resources Board of Trustees endorses recommendations to broaden research and education efforts within Texas Health following a yearlong evaluation of the system's research activity. The board subsequently approves a name change to The Research and Education Institute for Texas Health Resources (TREI).
2007: The Accreditation Council for Continuing Medical Education awards TREI Accreditation with Commendation for six years. Less than 10 percent of the national CME providers receive this level of accreditation.
2008: Hospital-based Institutional Review Boards (IRB) and research operations are consolidated under TREI. The systemwide electronic IRB goes live.
2009: The organization's name is changed to Texas Health Research & Education Institute.