Integrative Cardiovascular Physiology Laboratory (ICP)
The mission of the Integrative Cardiovascular Physiology Laboratory (ICP) is to conduct novel integrative (molecular to systems level) research focused on the function of the cardiovascular system in health and chronic disease. Our research aims to:
- Investigate novel mechanisms that regulate cardiovascular function in healthy adults
- Identify how these mechanisms contribute to cardiovascular function during stress (environmental extremes, physiological stress) and chronic disease (obesity, hypertension, heart failure)
- Determine the efficacy of interventions for improving cardiovascular function and functional capacity in the setting of chronic disease
- Other research interests include the regulation of oxygen transport and utilization in environmental extremes (high altitude, simulated space flight) and clinical conditions (heart failure).
Current Projects
- Sympathetic neural patterns and transduction in obesity-associated hypertension
- Vascular effects of Neuropeptide Y in health and hypertension
Current Research Opportunities
View our current research opportunities for:
Researchers
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Principal Investigators
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Postdoctoral Fellows / Residents
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Staff
Publications
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Adrenergic control of skeletal muscle blood flow during chronic hypoxia in healthy males
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Challenging the Hemodynamic Hypothesis in Heart Failure With Preserved Ejection Fraction: Is Exercise Capacity Limited by Elevated Pulmonary Capillary Wedge Pressure?
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Global REACH 2018: increased adrenergic restraint of blood flow preserves coupling of oxygen delivery and demand during exercise at high-altitude
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Mechanisms of sympathetic restraint in human skeletal muscle during exercise: role of α-adrenergic and nonadrenergic mechanisms
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Global Reach 2018 Heightened α-Adrenergic Signaling Impairs Endothelial Function During Chronic Exposure to Hypobaric Hypoxia
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Impaired oxygen uptake kinetics in heart failure with preserved ejection fraction
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Escape, lysis, and feedback: endothelial modulation of sympathetic vasoconstriction
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Amplification of endothelium-dependent vasodilatation in contracting human skeletal muscle: role of KIR channels
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Mechanisms of the Improvement in Peak VO2 With Exercise Training in Heart Failure With Reduced or Preserved Ejection Fraction
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Regulation of skeletal muscle blood flow during exercise in ageing humans