Open Studies
- Sympathetic neural patterns and transduction in obesity-associated hypertension (STU2020-0749)
- The vascular effects of neuropeptide Y in health and hypertension (STU-2022-0895)
- The effect of adiposity on muscle and microvascular function in HFpEF (STU-2024-0279)
Sympathetic neural patterns and transduction in obesity-associated hypertension (STU2020-0749)
Purpose
Research Study seeking individuals looking to learn about body weight and blood pressure
The study aims to understand the interaction between body weight and blood pressure. We will measure muscle sympathetic nervous system activity in people of all body sizes who have high blood pressure.
Qualifications for this research study:
- Must be between ages 18-55 (no restriction on body weight)
- Have high blood pressure (hypertension)
- Not taking medication for diabetes
Volunteers will receive:
- Health information related to blood work
- DEXA scan for body composition
- 24-hour blood pressure monitoring
- Monetary compensation for study participation
Study procedures include:
- Measurement of nervous system activity
- Handgrip exercise
- Breathing a low oxygen gas mixture, like being on the top of a tall mountain
- Blood draw
If you don’t meet the study criteria, do you know someone who does? Please feel free to forward this message to them.
Contact Information
IEEM Laboratory Integrative Cardiovascular Physiology
Phone: 214-345- 5359
Email: IEEMVascular@texashealth.org
Study conducted by:
Institute for Exercise and Environmental Medicine
Texas Health Presbyterian Hospital Dallas with UT Southwestern
UT Southwestern Medical Center IRB Number STU-2022-0749
ClinicalTrials.gov: NCT04838678
The vascular effects of neuropeptide Y in health and hypertension (STU-2022-0895)
Purpose
This study is being done to understand how high blood pressure (hypertension) influences vascular function. The study involves administration of different drugs that impact blood pressure to increase our understanding of the actions of a peptide produced naturally in the body called neuropeptide Y, that may contribute to hypertension in some people.
Qualifications for this research study:
- 18-40 years old
- Body mass index (BMI) less than 32 kg/m2
- Have high blood pressure (hypertension)
- Not taking medication for diabetes
Volunteers will receive:
- Health information related to blood work and blood pressure
- DEXA scan for body composition
- Monetary compensation for study participation
Study procedures include:
- Brachial artery catheter (similar to an i.v. but placed in an artery)
- Infusion of substances that increase or decrease blood pressure
- Measurement of nervous system activity
- Handgrip exercise
If you don’t meet the study criteria, do you know someone who does? Please feel free to forward this message to them.
Contact Information
IEEM Laboratory Integrative Cardiovascular Physiology
Phone: 214-345-5359
Email: IEEMVascular@texashealth.org
Study conducted by:
Institute for Exercise and Environmental Medicine
Texas Health Presbyterian Hospital Dallas with UT Southwestern
UT Southwestern Medical Center IRB Number STU-2022-0895
The effect of adiposity on muscle and microvascular function in HFpEF (STU-2024-0279)
Purpose
We are looking for participants to serve as a control group in a study that aims to understand how skeletal muscle quality and health changes with obesity and other cardiovascular diseases.
Qualifications for this research study:
- Healthy adults aged 18 years and older
- Not taking medication for diabetes
- Not taking blood thinners
- Do not smoke/vape
Volunteers will receive:
- Monetary compensation for study participation
Study procedures include:
- Skeletal muscle and fat biopsies on the leg
- MRI of leg at rest and during single leg exercise
If you don’t meet the study criteria, do you know someone who does? Please feel free to forward this message to them.
Contact Information
IEEM Laboratory Integrative Cardiovascular Physiology
Phone: 214-345-5359
Email: IEEMVascular@texashealth.org
Study conducted by:
Institute for Exercise and Environmental Medicine
Texas Health Presbyterian Hospital Dallas with UT Southwestern
UT Southwestern Medical Center IRB Number STU-2022-0895