Current Research Opportunities

Open Studies


Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Morphine

(IRB STU# 092017-070)

Purpose

This study, which is funded by the U.S. Army Medical Research and Material Command, is being done to better understand how morphine (a commonly used pain medication) will alter the capacity to tolerate a serious injury leading to major blood loss in humans.

In the laboratory, we simulate blood loss by having individuals lay down with their lower body in a chamber and reducing the chamber pressure for a short period of time.

Requirements to participate

  • 18 – 45 years of age
  • Healthy & non-obese
  • Body weight greater than or equal to 143 pounds
  • English speaking
  • No current or previous cardiac, neurological and/or metabolic illness
  • No current or past history of substance or alcohol abuse

Participation will require 3 study visits lasting ~13 hours in total. During the study visits, subjects will be given pain medication and participate in a number exams that measure bodily function and pain tolerance. Qualified individuals will be compensated.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.

Effects of Low Dose Ketamine on Cardiovascular Function

(IRB STU# 092019-1792)

Purpose

Our research laboratory is looking for individuals to participate in a study examining how a commonly used pain medication affects heart and blood vessel function.

Eligibility

  • English speaking
  • 18 - 45 years of age
  • Non-obese
  • Systolic blood pressure <140 mmHg
  • Diastolic blood pressure <90 mmHg
  • No current or previous use of anti-hypertensive medications
  • No current or previous cardiac, respiratory, neurological, or metabolic illness
  • Any known history of renal or hepatic insufficiency/disease
  • Pregnancy or breast feeding
  • Not a current smoker
  • No current or past history of substance abuse

Study timeline

Participation requires three study visits lasting up to ~13 hours in total. Qualified participants will be compensated.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.

Cooling Modalities in Burn Survivors

(IRB STU# 2020-0334)

Purpose

The purpose of this project is to identify modalities to attenuate excessive elevations in skin and internal body temperatures during physical activity in well-healed burn survivors.

Eligibility

  • English speaking
  • 18 - 65 years of age
  • Burn injuries covering 20% or more of their body surface area
  • Non-obese (body mass index of less than 32 kg/m2)
  • Systolic blood pressure <140 mmHg
  • Diastolic blood pressure <90 mmHg
  • No current or previous cardiac, respiratory, neurological, or metabolic illness
  • Any known history of renal or hepatic insufficiency/disease
  • Pregnancy or breast feeding
  • Not a current smoker

Study timeline

Participation requires up to five study visits lasting up to ~15 hours in total. Qualified participants will be compensated.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.

Heat Wave, Aging, and Cardiovascular Function

(IRB STU# 2019-1759)

Purpose

The purpose of this study is to assess the cardiovascular responses of the older individuals during exposure to heat wave conditions

Eligibility

  • 18–39 or >65 years of age
  • Non-obese
  • No current or previous history of cancer, cardiac, respiratory, neurological, or metabolic illness
  • Not pregnant or breast feeding
  • Not a current smoker or smoked regularly in the past 3 years

Study timeline

Participation requires up to four study visits lasting up to ~21 hours in total. Qualified participants will be compensated.

Contact Information

If you would like more information, please contact ieemthermoregulationTHD@TexasHealth.org at 214-345-6502.