*On April 23, 2021, the CDC and the FDA lifted the temporary pause on the Johnson & Johnson vaccine. A safety review found that a very rare, but serious condition called thrombosis with thrombocytopenia syndrome (TTS) can develop, causing blood clots and low blood platelets. Nearly all reports of this serious condition have been in adult women younger than 50 years old. Women younger than 50 years old should be aware of their increased chance of having TTS and that there are other COVID-19 vaccine options available for which this risk has not been seen. The CDC and FDA lifted the temporary pause because a review of the data found that the known and potential benefits of the Johnson & Johnson vaccine outweigh the known and potential risks of the vaccine.

**On June 23, 2021, the latest data on reports of mild cases of inflammation of the heart muscle and surrounding tissue called myocarditis and pericarditis following COVID-19 vaccination among younger people states that this is an extremely rare side effect, and only an exceedingly small number of people will experience it after vaccination. Importantly, for the young people who do, most cases are mild, and individuals recover often on their own or with minimal treatment. In addition, myocarditis and pericarditis are much more common if someone gets COVID-19, and the risks to the heart from COVID-19 infection can be more severe. (HHS)